International Conference on Innovations for the Elimination and Control of Visceral Leishmaniasis (IEC-VL)

JH-Institute of Molecular Medicine, Jamia Hamdard, New Delhi-67

Nov 28-30, 2018

Detailed Program

Venue: Holiday Inn, Aerocity, New Delhi

Conference Programme

DAY 1-28th November, 2018

08:00 – 08:30 

Registration

08:30 – 10:55

Inaugural speeches

Hon’ble VC + Chief Guest

Plenary Lecture:

Prof. Nirmal K. Ganguly
Former DG of Indian Council of Medical Research, New Delhi, India
Title:  Study for zero-walk in Leishmaniasis elimination in the Asian Subcontinent

Key Note Address:

Prof. Shyam Sundar
Banaras Hindu University, Varanasi, India              
Title: Developing tools for the management of Kala-azar in its hinterland

10:55 – 11:20

TEA

  • A. VL & PKDL– Current status from control to elimination

11:00-12:20

Chair

Simon Croft
London School of Hygiene and Tropical Medicine, London, UK

Co-Chair

Angamuthu Selvapandiyan
Jamia Hamdard, New Delhi

Suman Rijal
DNDi, New Delhi, India

Title:    Kala-azar elimination in South Asia: Impact of the efforts so far in Nepal.yxdjy

Rajib Chowdhury
National Institute of Preventive and Social Medicine, Bangladesh

Title:  A path achieved towards kala-azar near-elimination in Bangladesh.

Pradeep Das
The Rajendra Memorial Research Institute of Medical Sciences,   Patna, India

Title: Overview of VL in India,  Past and Present

E.E. Zijlstra
Rotterdam Centre for Tropical Medicine, Rotterdam,
Netherlands

Title:  PKDL a threat in kala-azar elimination strategy in Indian Subcontinent

B.  Impacts of Basic Science and Research – Genomics / Immunology / Epimodelling

12:20-13:40

Genomics & Basic Science

Chair

Hira Nakhasi
Food and Drug Administration, Silver Spring, USA

Co-Chair

Mitali Chatterjee
Biomedical Genomics Centre, Kolkata, India

Chhitar Mal Gupta
CDRI, Lucknow, India

Title: Myosin and profilin as possible drug targets in Leishmania

Jean C Dujardin
Institute Tropical Medicine, Antwerp, Belgium

Title: Novel methods to sequence parasite genome directly in clinical samples

Greg Matlashewski
McGill Univ, Montreal, Canada

Title: Development of CRISPR-Cas Genome Editing in Leishmania

Dan Zilberstein
Technion, Israel Institute of Technology, Israel

Title: Divergent regulatory subunit of protein kinase A has a role in intracellular development of Leishmania.

13:40 – 14:40

LUNCH

 

14:40 – 15:40

Immunology 

Chair

Jesus G. Valenzuela
The National Institute of Allergy and Infectious Diseases, NIH, Rockville, USA

Co-Chair

Shaden Kamhawi
The National Institute of Allergy and Infectious Diseases, NIH, Rockville, USA

Abhay Satoskar
Ohio State University, Ohio, USA

Title: The critical role of inflammatory monocytes in disease outcome of visceral leishmaniasis

Christian Engwerda
University of Queensland, Lucia, Australia

Title: Host-directed immune therapy to help eliminate and control VL

Mitali Chatterjee
Biomedical Genomics Centre, Kolkata, India

Title: Macrophage reprogramming and antigen presentation in PKDL

15:40 – 16:40

Epidemiology

Chair

Piero Olliaro
Intervention and Implementation research, Tropical Disease Research (TDR), WHO, Geneva, Switzerland

Co-Chair

Marleen Boelaert
Institute of Tropical Medicine, Antwerp, Belgium

Graham Medley
London School of Hygiene and Tropical Medicine, London, UK

Title: The pattern of diagnosed cases in time and space during elimination and post-elimination of VL in India

OP Singh
Banaras Hindu University, Varanasi , UP,  India

Title: Determinants of disease progression and role of asymptomatic Leishmania donovani infection in transmission

Nadira Karunaweera
Colombo University, Sri Lanka

Title: L. donovani variant that causes cutaneous leishmaniasis in Sri Lanka

16:40 – 17:20

Inauguration of Posters Anjali Nayyar, Global Health Strategies, New Delhi     

 

POSTER SESSION I and TEA

17:20 – 18:40

ORAL PRESENTATION FROM SELECTED INVESTIGATORS:  Concurrent Sessions in 2 halls

Hall A

Chair

Simon Croft
London School of Hygiene and Tropical Medicine, London, UK

Co-Chair

Javier Moreno
Institute of Health Carlos III (ISCIII), Spain

4 Speakers 15 min each

Swati Saha, University of Delhi South Campus, New Delhi
Angamuthu Selvapandiyan, Jamia Hamdard, New Delhi
Lloyd Chapman, London School of Hygiene and Tropical Medicine, London UK
-------

Hall B

Chair

Greg Matlashewski
McGill Univ, Montreal, Canada

Co-Chair

Hira Nakhasi
USFDA, Silver Spring, MD USA

4 Speakers 15 min each

Ruchi Singh, Institute of Pathology, New Delhi
Niti Puri, Jawaharlal Nehru University, New Delhi
Roberto Badaro, Federal University of Bahia, Brazil

18:40 – 19:40

PANEL DISCUSSION

Chair

Prof. N.K. Ganguly,
Former Director General, Indian Council of Medical Research, New Delhi, India

Members

Jamsheed Mohamed, WHO, New Delhi
Neeraj Jain, PATH, New Delhi, India
Sanjay Sarin, FIND, New Delhi, India
Liz Clyman, BM Gates Foundation, New Delhi
P.K. Sen, NVBDCP, New Delhi

20:00 – 22:00

Evening Reception: DINNER

DAY 2-29th November, 2018

08:30 – 09:10

Key Note Address

Marleen Boelaert,
Institute of Tropical Medicine, Antwerp, Belgium
Title:  Elimination success stories with other infectious diseases.

 

Chair

Simon Croft
London School of Hygiene and Tropical Medicine, London, UK

 

Co-Chair

Steve Reed
The Infectious Disease Research Institute, Seattle, USA

C.  The tools for control:   Drugs / Diagnostics / Vaccines / Transmission / Surveillance

09:10 – 10:10

Transmission

Chair

Mary Cameron
London School of Hygiene and Tropical Medicine, London, UK

Co-Chair

Pradeep Das
The Rajendra Memorial Research Institute of Medical Sciences, Patna, India

Alon Warburg
Hebrew University of Jerusalem, Israel

Title: Sandfly: New vector control measures

Shaden Kamhawi
The National Institute of Allergy and Infectious             Diseases, NIH, Rockville, USA

Title: Significance of Vector Challenge in Relation to Visceral Leishmaniasis Control: Deciphering Sand Fly-Transmitted Infections.

Jorge Alvar
DNDi, Geneva, Switzerland

Title:  The role of PKDL patients in the VL transmission in Bangladesh.

10:10 – 11:10
  

Diagnostics

Chair

Suman Rijal
DNDi, New Delhi

Co-Chair

Greg Matlashewski
McGill Univ, Montreal, Canada

Poonam Salotra
National Institute of Pathology, New Delhi, India

Title: Post kala-azar dermal leishmaniasis (PKDL): a roadblock in elimination of kala-azar.

Emily Adams
Liverpool School of Tropical Medicine, Liverpool, UK

 

Sakib Burza
Médecins Sans Frontières, New Delhi, India

Title: Diagnosis and management of VL-HIV coinfection within the elimination framework.

Isra Cruz
FIND, Geneva, Switzerland

Title: Unmet diagnostic needs in leishmaniasis.

11:10-11:50

POSTER SESSION II and TEA

11:50 – 13:30

Drugs  

Chair

Anuradha Dube
CDRi, Lucknow, India

Co-Chair

Syamal Roy
Indian Institute of Chemical Biology, Kolkata, India

Fabiana Alves
DNDi, Geneva, Switzerland

Title: Current and future perspectives for the development of innovative treatments for leishmaniasis

Poonam Salotra
National Institute of Pathology, New Delhi, India

Title: Drug Efficacy against PKDL

Neena Goel
Central Drug Research Institute, Lucknow, India

Title: Drug discovery to combat VL in India

Syamal Roy
Indian Institute of Chemical Biology, Kolkata, India

Title: Therapeutic role of cholesterol in experimental visceral leishmaniasis

Najibulla Safi
Ministry of Public Health, Afghanistan

Title: The role of Thermo-therapy in the treatment of CL

13:30 –14:30

LUNCH

14:30 – 16:30

Vaccines

Chair

Steve Reed
The Infectious Disease Research Institute, Seattle, USA

Co-Chair

Abhay Satoskar,
Ohio State University, Ohio, USA

Hira Nakhasi
Food and Drug Administration, Silver Spring, MD, USA

Title:  Second generation Leishmanization with a live attenuated markerless Leishmania vaccine candidate

Ali Khamesipour
Center for Research and Training in Skin Diseases and
Leprosy, Teheran, Iran

Title: Evaluation of leishmaniasis vaccine using leishmanization

Paul Kaye
University of York, UK

Title: Strategies for vaccine development 2018-2023

Javier Moreno
Institute of Health Carlos III (ISCIII), Spain

Title: Assessment of immunity against leishmaniasis

Steve Reed
The Infectious Disease Research Institute, Seattle, USA

Title: Clinical Development of Vaccines for Cutaneous and Visceral Leishmaniasis

Sanjai Singh
Gennova Biopharmaceuticals, Pune, India

Title: Production process of Leishmania live attenuated vaccine.

16:30 – 17:10

POSTER SESSION III AND TEA  

17:10 – 18:00

PANEL DISCUSSION II

 

Chair

Dr. P.K. Sen
NVBDCP, New Delhi

 

Co-Chair

 

 

Members

Amresh Kumar, PATH, New Delhi, India
Member, WHO, New Delhi, India
Mary Cameron, LSHTM, London, UK
Nirmal K. Ganguly, Former DG of ICMR, New Delhi, India
Nupur Roy, NVBDCP, New Delhi

DAY 3-30th November, 2018

08:00 – 8:40   

Key Note Address

Madubala Rentala
Jawaharlal Nehru University, New Delhi
Title: Career and how to involve new investigators

 

Chair

Serman Singh
AIIMS, New Delhi

 

Co-Chair

 

D. Data management / health systems / roles of public and private sectors / integration

08:40 – 10:20 

Chair

Nupur Roy
NVBDCP, New Delhi

Co-Chair

Sakib Burza
Médecins Sans Frontières, New Delhi, India

Thomas Dorto
DNDi, Geneva, Switzerland

Title: PK/PD as a tool for the development and optimization of new therapies for VL

Kingsuk Misra
KalaCore, Kolkata, India

Title: Public health 800013assessment during VL in India

Mary Cameron
London School of Hygiene and Tropical Medicine, London, UK

 

Philippe Guerin
Infectious Disease Data Observatory, University of Oxford, UK

Title: Collaborating to optimise the efficacy of VL therapies: a VL global data platform

Jose Postigo
World Health Organization, Geneva, Switzerland

Title:  The role of WHO in the visceral leishmaniasis control and elimination programmes in East Africa and South-East Asia

10:20 -10:40

TEA

10:40 – 12:40

ORAL PRESENTATION FROM SELECTED INVESTIGATORS:  Concurrent Sessions in 2 halls

Hall A

Chair

Chittar Mal Gupta
CDRI, Lucknow, India

Co-Chair

Ali Khamesipour
Center for Research and Training in Skin Diseases and Leprosy, Teheran, Iran

8 Speakers 15 min each

Serman Singh, AIIMS, New Delhi, India
Neelu Singh, CDRI, Lucknow, India
Farhat Afrin, Saudi Arabia
Vimal Kumar Varun, DSIR, DST, New Delhi

Hall B

Chair

Poonam Salotra
National Institute of Pathology, New Delhi, India 

Co-Chair

Nadira Karunaweera
Colombo University, Sri Lanka

8 Speakers 15 min each

Sushmita Das, AIIMS, Patna, Bihar, India
Anindita Ukil, Kolkata
Speaker from Sri Lanka
Speaker from Sri Lanka
Shailja Singh, Jawaharlal Nehru University, New Delhi, India

12:40 – 13:40

LUNCH

13:40 – 15:00

PANEL DISCUSSION III 

 

Chair

Dr. Piero Olliaro
Team Leader, Intervention and Implementation research, Tropical Disease Research (TDR), WHO, Geneva, Switzerland

15:00 – 15:30

TEA and DEPART

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